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Design of amyloidogenic peptide traps

Authors: Danny D Sahtoe, Ewa A Andrzejewska, Hannah L Han, Enrico Rennella, Matthias M Schneider, Georg Meisl, Maggie Ahlrichs, Justin Decarreau, Hannah Nguyen, Alex Kang, Paul Levine, Mila Lamb, Xinting Li, Asim K Bera, Lewis E Kay, Tuomas P J Knowles, David Baker

Journal: Nature Chemical Biology

PubMed ID: 38503834

Doi: 10.1038/s41589-024-01578-5

Products & Services: Gene Synthesis

Efficient production of isomaltulose using engineered Yarrowia lipolytica strain facilitated by non-yeast signal peptide-mediated cell surface display

Authors: Juanjuan Liu, Jiao Li, Peng Chen, Yan Zeng, Jiangang Yang, Yuanxia Sun

Journal: J Sci Food Agric

PubMed ID: 38436580

Doi: 10.1002/jsfa.13426

Products & Services: Codon Optimization

miR396b/GRF6 module contributes to salt tolerance in rice

Authors: Huanran Yuan, Mingxing Cheng, Ruihua Wang, Zhikai Wang, Fengfeng Fan, Wei Wang, Fengfeng Si, Feng Gao, Shaoqing Li

Journal: Plant Biotechnol J

PubMed ID: 38454780

Doi: 10.1111/pbi.14326

Products & Services: Molecular Biology Reagents

De Novo Multienzyme Synthetic Pathways for Lactic Acid Production

Authors: Xu-Wei Ding, Jing Rong, Ze-Peng Pan, Xin-Xin Zhu, Zhen-Yu Zhu, Qi Chen, Zhi-Jun Zhang, Jian-He Xu, Chun-Xiu Li, and Gao-Wei Zheng

Journal: ACS Catal

Doi: doi.org/10.1021/acscatal.3c05489

Products & Services: Codon Optimization

The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation

Authors: Hang Xu, Zihao Yuan, Kunpeng Qin, Shuai Jiang , Li Sun

Journal: Elife

PubMed ID: 38489483

Doi: 10.7554/eLife.89974

Products & Services: Proteins, Expression, Isolation and Analysis

An Insertion Within SIRPβ1 Shows a Dual Effect Over Alzheimer’s Disease Cognitive Decline Altering the Microglial Response

Authors: José María García-Alberca, Itziar de Rojas, Elisabeth Sanchez-Mejias , Diego Garrido-Martín

Journal: 1

PubMed ID: 38427484

Doi: 10.3233/JAD-231150

Products & Services: Gene Synthesis

Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs

Authors: James Jiqi Wang, Sanshan Jin, Heng Zhang, Youwei Xu, Wen Hu, Yi Jiang, Chen Chen, Dao Wen Wang, H Eric Xu, Canrong Wu

Journal: Sci Adv .

PubMed ID: 38335293

Doi: 10.1126/sciadv.adk5184

Products & Services: Proteins, Expression, Isolation and Analysis

SRRM2 phase separation drives assembly of nuclear speckle subcompartments

Authors: Mengjun Zhang, Zhuang Gu, Shuanghui Guo, Yingtian Sun, Suibin Ma, Shuo Yang, Jierui Guo, Chenxi Fang, Li Shu, Yifan Ge, Zhongwen Chen, Bo Wang

Journal: Cell Rep .

PubMed ID: 38381607

Doi: 10.1016/j.celrep.2024.113827

Products & Services: Proteins, Expression, Isolation and Analysis

N-homocysteinylation of DJ-1 promotes neurodegeneration in Parkinson's disease

Authors: Tao Guo, Lingyan Zhou, Min Xiong, Jing Xiong, Juan Huang, Yiming Li, Guoxin Zhang, Guiqin Chen, Zhi-Hao Wang, Tingting Xiao, Dan Hu, Anyu Bao, Zhentao Zhang

Journal: Aging Cell

PubMed ID: 38380563

Doi: 10.1111/acel.14124

Products & Services: Proteins, Expression, Isolation and Analysis

Engineering Anti-CRISPR Proteins to Create Cas12a Protein Switches for Activatable Genome Editing and Viral Protease Detection

Authors: Wenyuan Kang, Fei Xiao, Xi Zhu, Xinyu Ling, Shiyi Xie, Ruimiao Li, Peihang Yu, Linxin Cao, Chunyang Lei, Ye Qiu, Tao Liu , Zhou Nie

Journal: Angew Chem Int Ed Engl .

PubMed ID: 38407550

Doi: 10.1002/anie.202400599