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    目录产品 » PD-1 Antibody (2E5), mAb, Mouse

    PD-1 (2E5), mAb, Mouse

    Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.
    V02201
    询价

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    Description

    Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.
    Subclass IgG1
    Host Species Mouse
    Conjugation Unconjugated
    Antigen Species Human

    Production Cultured in vitro under conditions free from animal-derived components
    Purification Protein A/G affinity column
    Formulation 1) PBS, pH 7.4, containing 0.03% Proclin 300
    2) 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% Proclin 300 *
    *: For new batch since 09/01/2018, please refer to COA.
    Concentration ≥2mg/ml
    Clone ID 2E5
    Storage For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.


    Target Background Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.

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