Description
Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. |
Synonyms
B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7
Applications |
Binding assay or use as immunogen |
Storage |
Liquid nitrogen immediately upon receiving |
Species |
Human |
Stability |
15 passages |
Freeze Medium |
95% complete growth medium, 5% DMSO |
Culture Medium |
F12K, 10% FBS, 8 μg/ml Puromycin |
FACS analysis of CD80 expression in CHO-K1/CD80 cells.
FACS analysis of CD80 expression in CHO-K1/CD80 cells.
FACS analysis of CD80 expression in CHO-K1/CD80 cells.
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