Description
BDCA-2 is a novel type II C-type lectin, which shows 50.7% sequence identity at the amino acid level to its putative murine ortholog, the murine dendritic cell–associated C-type lectin 2. In addition to its antigen capturing function, BDCA-2 can mediate potent inhibition of induction of IFN-α/β expression in PDCs. Production of IFN-α/β in response to several different types of viruses, bacteria, CpG-DNA, dsRNA, and SLE serum is by far the most prominent feature of PDCs. |
Applications |
Binding assay or use as immunogen |
Storage |
Liquid nitrogen immediately upon receiving |
Species |
Cyno |
Stability |
15 passages |
Freeze Medium |
95% complete growth medium, 5% DMSO |
Culture Medium |
F12K, 10% FBS, 8 μg/ml Puromycin |
FACS analysis of Cyno BDCA2 expression in CHO-K1 cells.
FACS analysis of Cyno BDCA2 expression in CHO-K1 cells.
FACS analysis of Cyno BDCA2 expression in CHO-K1 cells.
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