PACAP (1-38), human, ovine, rat

PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.

产品编号	RP10335CN
规格	0.5 mg 定制报价
数量
价格	￥1400


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产品概述

Description	PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10^-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10^-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.
Cas No	137061-48-4
Sequence	{HIS}{SER}{ASP}{GLY}{ILE}{PHE}{THR}{ASP}{SER}{TYR}{SER}{ARG}{TYR}{ARG}{LYS}{GLN}{MET}{ALA}{VAL}{LYS}{LYS}{TYR}{LEU}{ALA}{ALA}{VAL}{LEU}{GLY}{LYS}{ARG}{TYR}{LYS}{GLN}{ARG}{VAL}{LYS}{ASN}{LYS}-NH₂
Sequence Shortening	HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH₂
Molecular Formula	C₂₀₃H₃₃₁N₆₃O₅₃S₁
C Terminal	NH₂
Molecular Weight	4534.26

产品属性

Purity	> 95%
Solubility	The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
Form	Lyophilized
Storage	Store the peptide at -20°C.
Note	PACAP stimulates adenylate cyclase in rat anterior pituitary cells.