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    TNF-α, Human

    GenScript product showed better activity compared to competitor P

    TNF-α, Human

    GenScript product showed better activity compared to competitor R

    TNF-α, Human

    Biological Activity
    TNF-alpha, Human (Cat. No. Z01001) stimulates cytotoxicity of L-929 mouse fibrosarcoma cells. The ED50 for this effect is typically 11-50 pg/mL.

    TNF-α, Human

    2 μg of TNF-α, Human (Cat. No. Z01001) was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie Blue staining.

    TNF-α, Human

    Tumor Necrosis Factor-alpha (TNF-a) is a homotrimer with a subunit molecular mass of 17.3 kDa. Tumor Necrosis Factor-alpha(TNF-a) plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn's disease, and rheumatoid arthritis as well as graft-versus-host disease.
    Z01001
    ￥400

    163am银河线路娱乐官网
    Species Human
    Protein Construction
    TNF-α (Val77-Leu233)
    Accession # P01375
    Purity > 98% as analyzed by SDS-PAGE
    > 98% as analyzed by HPLC
    Endotoxin Level < 0.2 EU/μg of protein by gel clotting method
    Biological Activity ED50 < 30.0 pg/ml, measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D, corresponding to a specific activity of > 3.3 × 107 units/mg.
    Expression System E. coli
    Apparent Molecular Weight ~17.3 kDa, on SDS-PAGE under reducing conditions.
    Formulation Lyophilized after extensive dialysis against PBS.
    Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml.
    Storage & Stability Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

    • TNF-α, Human
      • TNF-α, Human

      GenScript product showed better activity compared to competitor P

    • TNF-α, Human
      • TNF-α, Human

      GenScript product showed better activity compared to competitor R

    • TNF-α, Human
      • TNF-α, Human

      Biological Activity
      TNF-alpha, Human (Cat. No. Z01001) stimulates cytotoxicity of L-929 mouse fibrosarcoma cells. The ED50 for this effect is typically 11-50 pg/mL.

    • TNF-α, Human
      • TNF-α, Human

      2 μg of TNF-α, Human (Cat. No. Z01001) was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie Blue staining.


    Target Background Tumor Necrosis Factor-alpha (TNF-a) is a homotrimer with a subunit molecular mass of 17.3 kDa. Tumor Necrosis Factor-alpha(TNF-a) plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn's disease, and rheumatoid arthritis as well as graft-versus-host disease.
    Synonyms TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin; DIF; TNFA; TNFSF2

    For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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